IONS Ionis Pharmaceuticalsdata gap · 64% coveragelimited data
Health Care · Pharmaceutical Preparations · close $42.94 (2026-10-16) · latest quarter in EDGAR: 2026-06-30
Ionis Pharmaceuticals (IONS) has a ThetaGrade House Rating of 20/100 (grade F), ranking #149 of 150 in Health Care. Its strongest pillars are balance sheet (53) and valuation (24); its weakest is growth (3). Data gap: 5 factors without usable data, so 64% of the method weight is covered. TTM revenue growth is -7.4% and operating margin -68.0%.
Data as of .
Data gap
No usable data for: Consensus score (1–5), 90-day net rating shift, EPS growth YoY (TTM), Net debt / EBITDA, P/E (inverted). Data gap: no usable data for this factor, so it is left out and its weight is shared among the factors that do have data (no value is imputed). 64% of the full method weight is backed by data.
Analyst sentiment
weight 7.5% · no data · —| Consensus score (1–5) (0.0%)data gap | derived | — |
| 90-day net rating shift (0.0%)data gap | derived | — |
Growth
weight 30.83% (→33.3%) · 3| Revenue growth YoY (TTM) (22.2%) | -7.4% | 4 |
| EPS growth YoY (TTM) (0.0%)data gap | — | — |
| Revenue acceleration (11.1%) | -127.7% | 2 |
Profitability
weight 18.5% (→20.0%) · 19| Operating margin (10.7%) | -68.0% | 10 |
| 4Q gross-margin change (9.3%) | -0.7% | 30 |
Balance sheet
weight 18.5% (→20.0%) · 53| Net debt / EBITDA (0.0%)data gap | — | — |
| Current ratio (11.4%) | 7.89 | 87 |
| Interest coverage (8.6%) | -34.43× | 7 |
Cash flow
weight 12.33% (→13.3%) · 10| FCF margin (6.7%) | -33.9% | 10 |
| FCF yield (6.7%) | -4.5% | 9 |
Valuation
weight 12.33% (→13.3%) · 24| P/E (inverted) (0.0%)data gap | — | — |
| EV/Sales (inverted) (13.3%) | 9.78× | 24 |
Technicals (EOD)
| RSI(14) | 37.7 |
| EMA 9 / 21 | 43.60 / 45.32 |
| 200-day SMA | 68.60 |
| Volume vs 20d avg | 0.46× |
| 20-day return | -8.1% |
Exit-rule monitor
- EXITRating break: House Rating below 60
- EXITFundamental miss: revenue growth negative YoY
- EXITBalance-sheet stress: negative free cash flow (latest FY)
- WATCHTrend: close below 200-day average
Data source per metric (SEC XBRL tag or derivation): Revenue: RevenueFromContractWithCustomerExcludingAssessedTax · Gross profit: Revenue − CostOfGoodsAndServicesSold · Operating income: OperatingIncomeLoss · Interest expense: InterestExpense · D&A: Depreciation · EPS: EarningsPerShareDiluted · Market cap: SEC shares (dei EntityCommonStockSharesOutstanding (cover page)) × EOD close.
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FAQ
- What is IONS's House Rating?
- IONS scores 20 out of 100 (grade F) as of 2026-10-16, ranking #149 of 150 Health Care stocks we cover.
- What do analysts say about IONS?
- We do not have enough analyst-sentiment data to score this stock.
- When does IONS report earnings next?
- IONS's next earnings report is estimated for about 2026-10-28 (window 2026-10-21 to 2026-11-04), based on its past SEC 8-K earnings filings. This is an estimate, not a company-confirmed date.
- Is IONS a buy?
- ThetaGrade does not give personal advice. The House Rating is an educational, rules-based summary of public data; see the methodology for how it is built.
Sources: SEC EDGAR filings (fetched 2026-10-18), Finnhub recommendation trends, Massive EOD prices. Scores are sector percentiles; a factor without usable data is a data gap: it is left out and the remaining weights are renormalized (nothing is imputed). Educational only. Methodology